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In an amazing turn of events, county commissioners in two key New Mexico counties have taken giant political steps to revive the Nuclear Renaissance in this state. Concerns about the energy crisis, dependence upon foreign oil and global

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

warming have recently led many politicians to suggest alternatives, namely nuclear energy. The record uranium price also helps bring big dollars into their local economies. Both counties are blessed with abundant uranium resources, which

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

they are now encouraging to be mined.

What was once the world’s top producing uranium area, the Grants Uranium District has largely slumbered through the emerging uranium boom of the past three years. Stock analysts and investors discou

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

ted efforts by those uranium mining companies which have been moving their flagship projects forward, primarily Uranium Resources (URRE) and Strathmore Minerals (STHJF). In light of these developments, their opinions could soon change.

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

his past September, Cibola County passed a resolution supporting and encouraging uranium mining. The county clearly believes the renewal of uranium mining would provide a strong economic boost for its residents. This resolution did not s

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

rprise us. We first reported on the pro-uranium pulse of Grants (New Mexico) and Cibola County in late June 2005. The county’s head of economic development told us, “We will greet them (uranium miners) with open arms.” And then they did

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

n both county and city resolutions which followed three months later.

What DID surprise us was the nearly identical resolution passed by McKinley County Commissioners. Having traveled through this county and interviewed various personal

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

ities, the county-wide resolution amounts to nothing short of a miracle. That’s because the adjacent Navajo Nation, in the four corners area (New Mexico, Utah, Colorado and Arizona), banned uranium mining in 2005. The city of Gallup is M

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

Kinley’s county seat. Gallup’s Wal Mart is reportedly where the Navajos do most of their shopping. More than 36 percent of Gallup’s residents are Navajo.

Even more amazing is the fact that McKinley County Commissioner Ernest C. Becenti,

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

Jr, the gentleman who introduced McKinley County Resolution Number DEC-06-088 for consideration by the County Commission, is a Navajo. One of the primary reasons cited in the resolution was to replace the economic loss the county will su

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

fer when the Pittsburgh & Midway coal mine shuts down in 2008. This resolution is likely to have a broad impact within the Navajo community in Gallup because it will help replace those lost mining jobs.

We talked with Mark Pelizza, vice

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

president of environmental affairs for Uranium Resources, who told us, “We are pleased the principals of McKinley County understand the economic benefits of uranium mining.” How big is it? “The potential impact is huge,” Pelizza said, “A

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

$100/pound and 10 million pounds U3O8 produced annually, it could bring $1 billion in uranium sales to the local economy.”

Strathmore Minerals’ vice president of environmental affairs Juan Velasquez wrote in an email, “We have enjoyed

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

lot of grass roots support from the folks in the Grants area, and we are heartened that McKinley County is favorable to our activities.” The resolutions should impact both companies in 2007 because they were the first to commence the re

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

quired activities to obtain uranium mining licenses.

Uranium Resources has been actively involved in New Mexico since 1986, according to Pelizza, and obtained its NRC approval in the mid 1990s (recently reaffirmed by the NRC). Strathmor

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

Minerals opened its environmental permitting office in 2005 and has been progressing through the state and federal permissions activities for two of its New Mexico uranium properties.

Over the past year, several other uranium companies

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

became more active in the Grants Uranium District, such as Urex Energy (OTC BB: URXE), Laramide (LMRXF) and Western Uranium (WURNF). Another advanced stage junior uranium mining company, Energy Metals Corp (EMU) also holds properties in

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

ew Mexico, but decided to first develop its projects in Texas and Wyoming.

This past June, New Mexico State Senator Joseph A. Fidel, who represents one of the counties in the Grants Uranium District, told StockInterview, “The community

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

ill be very supportive of uranium mining. People will be cooperative and will react positively, when the time comes.” In June, the U.S. Nuclear Regulatory Commission issued LES a draft license to build and operate the first U.S. uranium

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

nrichment facility in more than thirty years. It appears New Mexico’s time has come, and this state is back on track to revive its formerly world-class uranium mining industry.

COPYRIGHT © 2007 by StockInterview, Inc. ALL RIGHTS RESERVE

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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