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Bulls and bears.

Firstly the bull is a buyer and the bear is “always” a sell

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

er.

The bull buys because he wants to make money, (don’t we all?).

The bear

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

is more complicated and can sell for different reasons. This can be just to

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

lock in a profit because he thinks the share price is about to go down.

The

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

most fearful of the bears sets the lowest price for the day. This is done by

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

offering to sell his shares at this level.

In a “bull market” novice traders

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

rush into every reasonable opportunity they can afford.

These trades are no

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

based on good management or risk control.

Please try not to get caught up i

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

n this market hype. If you start to chase prices upwards there is a very good

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

chance you will pay too much for them, only to watch the share price start t

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

o recede when the buying panic is over.

Sounds familiar? I know this one by

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

bitter experience.

The share price went down and still I held on hoping they

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

would start to go upwards again. I went past my stop loss level {(I forgot t

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

o put one on in the panic to buy shares Still telling myself it would retra

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

e. It did but 2 months later so feeling very thankful I sold making a 7 1/2%

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

profit.

Those shares today 2 years on are now worth 200% more. I was too fri

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

ghtened to buy back in again in case the same thing happened again.

That was

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

a hard lesson to learn. Plus with that money tied up $2,000 worth, I missed

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

out on a few bargains in those two months which would have made me a minimum

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

of $650 profit more than if I had got out at my stop loss level of 10%($200)

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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