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    1. Assessing the risk: - The longer you are in the trade, (you own the stock) the more the chance increases of a reversal in the share price. If you are in for Long Term than this is not so an
    According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product
    important factor.

    2. Time factors. Are the stocks for short, long term or medium term? This is crucial because it will save you time, effort and worry later on.

    3. How many shares do you need
    ; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

    Examples of combination products may in
    to make it a viable financial proposition? Again in medium to long term again it is not so important.

    4. The minimum amount you can buy on the ASX is $500.00 now an important factor to consid
    lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

    er is that on average the brokerage for buying and selling will amount to $50.00. Now that is 10% profit that you have to make just to break even.

    Therefore a 20% profit will gain you $100.00
    here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe
    less brokerage of $50.00 leaves you the sum of $50.00 profit. We haven’t taken into account capital gains yet. That you worry about when you are making a profit and not before.

    Not much you s
    d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

    Combination pro
    ay, and I agree with you. But if funds are limited as mine were to start with, you need 10 successful trades to make $500.00.

    And do not think that is easy. I can tell you now that I averaged
    ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc
    only around the 60% success rate to begin with in the first six months.

    My knowledge was very meager, and only basic information could be found without having to pay for it. (A website like th
    easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi
    is one where detailed information is free were very hard to find.) And aren’t you “Lucky” that you found this website?

    5. The next point to consider is movement. (Volatility) In other words h
    nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically
    ow many shares are being traded on a daily/weekly average?

    You don’t want to be buying a share that is hard to sell, particularly if the share price drops. Which on the odd occasion they are p
    and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ
    rone to do at times, without any prior warning.

    6. If the share price is for a “Blue Chip” say around $5.00 to $10 .00 then at $500.00 you will only get around 100 to 50 shares.

    Of course th
    ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi
    e lower price the share costs the higher amount of shares you get for your dollar.

    Now a funny thing happens here as the price of the shares get cheaper the “Risks Increase” This due to a larg
    ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

    Following aspects would a
    er increase in Volatility and the Volume of shares sold.

    Blue chips maximum movement is usually around the 10% i.e. a $20.00 share will move around $2.00 (this also depends on market sentiment
    dd to the challenges in developing combination products:

    Which markets to tap where the combination products can do fairly well?
    Which combination prod
    .) While a Green chip stock’s price movement is usually in the 20% to 50 % range.

    When you come to the lower priced stocks this includes your “speculative” stocks. The higher volume is around
    cts are meaningful and rational?
    Which therapeutic categories to select?
    Which Combinations can address unmet needs of the patients?
    Do combin
    the 50% to 100%

    These are not hard and fast rules as there are other variables to consider i.e. is it a “Bull or “Bear” market? (Is it a buyer or a sellers market?)

    Large profits are made at
    tions increase the patient compliance?
    What would be the developing cost?
    How to tackle the risks encountered during combination product developmen
    this end of the market, but bear in mind the risks are equally great and can result in big losses for the unwary.

    7. A most important tool used is a “Stop Loss.” This is used to minimize your
    t?

    As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel
    losses if a trade goes bad. (Downwards)

    8. Discipline. This is done by doing “YOUR” research (and not relying on so called “Hot Tips”) this is done by employing either basic “Fundamental Anal
    ping new procedures for reviewing their safety, efficacy and quality.

    Professional from academic institutions, pharmaceutical industries, health care indust
    ysis” or “Technical Analysis.”

    The first is done by checking out the company itself.

    Whilst the second is using past information in the form of using “Charts” to help you towards making an ed
    y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products
    ucated decision. Prior to your share purchase.

    I personally use a mixture of both. But what works for me might not work for you. What suits you best will only be found out by doing it and tria
    .

    As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de
    l and error.

    I am continually “honing” my skills and have learnt by making mistakes and then not repeating those mistakes again.

    And yes! I still stuff up but not so often lately. But I don’t
    elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

    Companies that provide selfless information through particip
    think I know it all either, for I don’t, so I am constantly learning on a Daily basis.

    I hope this post has been of some assistance to you and improves your skills in picking “Winning Shares.


    tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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