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Many Americans look forward to the day they send in their last mortgage payment and own their home free and clear. They can spend their

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

senior years secure in the knowledge that as long as they pay their property taxes, their most valuable asset is safe. When they die,

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

they can pass their home on to their children, grandchildren, or other heirs. It’s a heartwarming picture, right out of a Thomas Kinkai

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

d painting. But wait. What is that dark shape lurking outside, casting a shadow across the ivy-framed door?

It’s a Medicaid reimbursem

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

ent official, lien in hand, ready to seize your family’s greatest asset. Is this some artist’s dark fantasy? Not at all. Most states ha

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

ve laws that allow them to seek reimbursement for Medicaid payments. Your home is exempt from recovery, but only as long as you live in

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

it. The day you enter a nursing home on a permanent basis, that protection flies out your warmly glowing window.

If you are married,

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

our house will remain exempt as long as your spouse lives in it. Should your spouse die, the state can place a lien on your home. With

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

the lien in place, you can neither sell the house nor refinance it without reimbursing the state for your Medicaid payments. The state

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

can enforce its lien upon your death. If what you owe equals the equity in your house, your heirs will receive nothing from the sale of

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

your home. What can you do? Here are a couple of suggestions:

1. Get long ter

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

m care insurance. It will pay for in-home care, a stay in a nursing home, or a stay in an assisted living facility, so you never ha

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

ve to resort to using Medicaid. Chances are good that you will use such insurance. According to the American Association of Homes and S

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

ervices for the Aging, 69% of Americans who live to be 65 will require long term care at some point.

2. Give your home to your childre

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

or other loved ones. The state cannot place a lien on the home if it is not yours. Be careful, though. The gift must be made more than

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

36 months before you enter a long term care facility. In addition, this action may have tax consequences for the person receiving the

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

gift.

3. Transfer the home using a special power of appointment. With this strategy, you transfer the ownership of your home to someon

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

e else, keeping it away from the state. You can have the transfer occur during your lifetime or upon your death. You can reserve the ri

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

ght to change your mind and redirect the home to someone else.

Designing a Medicaid strategy is complicated. There are many options, s

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

o consult with an attorney who specializes in elder law. Or get long term care insurance and paint Medicaid out of the picture entirely

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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Marketing is one of the most important factors facing your business each day. When you think about it, marketing has a direct impact on every factor involved with your ultimate success or failure. With this in mind, it becomes obvious that a healthy advertising strategy is vital to the health of your business.

Anyone, regardless of age, sex, colour, or any other characteristic can become an entrepreneur. There are no limitations on this form of economic expression. Entrepreneurship is not a generic trait; it is a skill that must be learned.

Retail sector is the second largest industry in U.S., accumulating number of businesses and employees. According to the government broad measure of retail sales that consists food service, gasoline sales and automobiles) sales in the U.S. climb nearly 6.6% to $4.16 trillion in 2005, comparing a 3.8% increase in the year 2004. In the last year, retail industry evolved strongly, due to higher gasoline costs and good discounting during the Christmas.

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