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Law enforcement agencies, commonly called the police, are tasked by the government

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

to protect and serve the people. Proper equipment is a vital component of an effe

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

tive law enforcement body.

Standard equipment issued to a police officer includes

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

a gun, a holster for the gun, handcuffs, a nightstick, and a two-way transmission

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

adio. The gun issued is only to be used if the officer is fired at. By no means sh

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

uld a police officer shoot first shot unless he or the other people around him are

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

in danger. The handcuffs are to be used to restrain an assailant. The nightstick i

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

a non-lethal weapon that an officer can utilize to defend himself.

A traffic enf

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

rcer is assigned a radar gun used to determine the speed of vehicles. To keep the

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

eace during a riot, police officers are issued helmets and shields to protect them

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

while they control the crowd. If the crowd becomes too unruly, the officers might

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

be forced to use tear gas or to borrow water cannons from the fire department.

Bu

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

tear gas is not only used by riot police. It is actually a standard part of the a

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

senals assigned to a Special Weapons and Tactics (SWAT) officer. SWAT members are

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

ssigned more specialized weaponries for the most dangerous missions. The situation

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

that these officers engage in are often life-threatening. They are issued bulletp

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

oof vests and night vision goggles. Members of the SWAT team do not always go dire

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

tly to the front lines. If necessary, they can attack from afar using sniper rifle

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

.

Equipment does not make an officer. Using police equipment requires sufficient

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

raining, discipline, and the ability to make the right decisions in a split-second

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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