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A week ago I received an auto-responder from an U.S. University informing me that the person I contacted was on leave at that moment and would get back to me as soon as he was at the office again. What made my eyes pop out of their socket

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

s was the subject of e-mail they were referring to. Someone sent this person an e-mail about something I don’t even want to mention here, an e-mail, according to them, that was sent from my e-mail address associated with my cyber-security

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

web site. This has been a clear case of identity theft. I guess the spammer who sent the original message did not think I would get an auto-responder informing me about it. I was lucky in this specific case because you never know how much

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

people send e-mails under your own e-mail address.

Some advice to webmasters. Never use the “mailto” tag on your web pages. Spam spiders crawl your website looking for e-mail addresses and specifically “mailto” tags. You make it too easy

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

for spammers to get your e-mail address when you use “mailto” tags. Rather embed your e-mail address in an image with a font that is readable to your visitors and at the same time hard to be converted to text by spam spiders. This will de

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

rease the chances of having your e-mail address spoofed in some kind of spam e-mail and you will also have a smaller chance of receiving spam. This is not foolproof, but will certainly fool less advanced spam spiders.

Never reply to spam

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

e-mails. Many spam e-mails contain a spoofed e-mail address. You will only supply your e-mail to somebody you don’t know a thing about and the best of all, the person may not even be associated with the e-mail in the first place. Other s

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

ammers count on the possibility that you reply to their message in order to confirm that your e-mail address is active. If you ignore their e-mail you will have a better chance of not receiving an e-mail from them in the future. The vast

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

ajority of spam e-mails do not even contain a valid e-mail address you can reply to. Your reply will most of the times bounce back. It is also dangerous to click on the links of spam e-mails. They sometimes link to web sites that contain

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

alicious software that will turn your innocent computer into a spamming device to do their dishonest promotion work for them.

National lottery e-mails are nothing other than information harvesters. You normally have to supply your social

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

security number or some kind of identification number, telephone numbers, postal addresses, fax numbers, e-mail addresses, even physical addresses. You can’t win a lottery if you haven’t entered one and even if you entered one you should

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

have lottery numbers that correspond with the ones in the e-mail. Lottery competitions normally work on a basis of collecting your prize with a valid lottery ticket. You never receive a notification via e-mail that you have won, you have

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

o watch television or read the newspaper to see if you have the winning numbers. Never reply to these e-mails or phone the numbers supplied in them, these people are only harvesting your personal information, nothing else.

Chain letters

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

s another way of getting your identity stolen. Ever noticed the large number of e-mail addresses contained within chain letters, especially if they have come a long way? By forwarding chain letters to all your contacts, not only makes you

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

self guilty of spamming, you also walk the risk of supplying your e-mail address to other spammers.

Petition lists is a very clever way of harvesting personal information. These lists are normally about sensitive matters that stir up emo

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

ion from the readers in order to move them to forward the list with their name and contact details to everyone they know. Petition lists normally have a statement that if you are, lets say number 100, on the list you have to send the list

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

back to person listed at the top. Now think clearly about this. Lets say you are number 50 on the list and you forward this to 5 other people and each of them forward the list to 5 persons each. You end up with multitudes of the same lis

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

, where the first 50 people on the list are the same every time. Do you really think the creator of this list is going to filter trough all these lists and remove all the duplicate entries? No, petition lists is only a way of creating a n

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

ver-ending source of personal information for spamming and illegal activities.

The FBI is stepping up its fight against online fraud with a new initiative called Operation Identity Shield. It is nice to see the authorities doing somethin

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

about this, but the root of the problem still lies with the uninformed Internet users. If you don’t have the knowledge to identify these threats, you will take part in identity theft practices without even knowing the dangers they impose

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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