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Asbestos was once regarded as a wonder substance due to its heat resistant properties. It was, therefore, a w

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

idely used material, particularly from the 1930’s – 1980’s and exposure still continues wherever it is distur

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

ed / removed.

The cost of asbestos claims in the UK could reach ?20 billion in the next 30 years.

Claims ca

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

be made by Claimants, even though the exposure was 30 or more years ago, and the past employer(s) has gone o

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

ut of business.

Claims can also be made for deceased Claimants on behalf of their loved ones/estate.

Succes

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

ful ‘secondary’ claims for Asbestos exposure have been made by spouses, children and grandchildren, after the

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

were exposed to harmful fibres on work clothes worn home.

The compensation obtained can, in many cases, amo

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

unt to well in excess of ?100,000, depending upon the severity of the particular disease.

Asbestos has no re

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

pect for socio-economic group or occupation. There are over 1,000 new cases of Mesothelioma reported every y

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

ar in the UK. It is generally accepted asbestos is the cause.

The types of occupation where exposure can be

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

found/occur include the following:-

Asbestos Cement Products Industry (used for strong, inexpensive

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

building materials, eg tiles, corrugated roofing, gutters, water and drain pipes, chimneys etc.

Floor

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

tiling industry

Insulation and Fire Proofing

Carpenters

Electricians

Power Pl

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

nt Works

Plumbers

Roofers

Central Heating and/or air conditioning contractors

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

>School and Hospital workers

Ship workers

Symptoms can include breathlessness and persiste

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

t coughing which may cause sleepless nights leading to fatigue. Some sufferers report chest pain and feeling

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

as though a heavy weight is pressing down on their chest, depending upon the particular condition.

There are

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

a number of state benefits available to victims and their carers. A specialist Solicitor can not only pursu

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

compensation claims for sufferers on a true No Win, N

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

Fee basis, but also provide advice and assistance with applications in order to maximise benefit entitlement

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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