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The first phase of the long awaited for championship golf courses in Messinia, Greece is now under way. Construction work on the 18 hole state of the art luxury golf course at Romanos was started in

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

September 2006, by The Tourism Enterprise of Messinia (TEMES). Troon Golf, the world’s leading high-end golf development, marketing and management company will be managing both the championship and st

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

andard courses. The golf courses themselves are being designed by Robert Trent-Jones II Inc the Californian based Golf Course Architects.

The opening of the course at Romanos will be in spring 2008

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

and is set to be a grand affair with many public personalities and it will also be televised. The construction of the second Phase at Pylos will commence in spring 2008 and the third phase at Rizomil

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

o will begin in spring 2010. Achilles Constantakopoulos, the Managing Director of TEMES has stated that by 2015, Navarino will be Greece’s premier golf destination. There will be seven courses within

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

half-an-hours drive of each other. In fact it will be the largest golf resorts in the whole of the Balkans and Mediterranean.

A large amount of land surrounding Romanos and Pylos has already been br

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

ought up by the ship owner who is developing the courses. A total of approximately 1.2 million m2 of land has been acquired from 1,300 individual holders of deeds. As a consequence it is becoming ha

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

rder to find building plots and houses near the golf courses. Those that are left are commending very high prices.

In the passed year property prices near Romanos and Pylos have increased rapidly and

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

the trend is set to accelerate still further. Government studies have shown that more than 200,000 visitors to Greece annually are potential golf tourists. It seems that many of these golfers are l

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

ooking for property near the courses and are adding to the frenzy of property hunter that are now flocking to the area.

As property near the courses at Romanos and Pylos grows ever scarcer property h

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

nters are being forced to search further a field than they anticipated. The areas that are benefiting most from increased interest are Methoni, Evagelismos and Finikounda.

The private sector investo

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

rs have been buying large parcel of land in Messinia and have been building holiday rental units. It is estimated that over the next 3 year the seaside town of Finikounda alone will have accommodation

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

for over 2000 tourists. Tourists will also benefit from a new Thalasso therapy centre (seawater treatments) that will soon be completed. Evagelismos a beautiful authentic Greek village which centre

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

s around its whitewashed church, cafes shaded by trees, a fountain and several shops creating a lively atmosphere. With its beautiful views across the surrounding countryside and of the islands that a

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

re scattered along the southern coast line has become a hotspot for people looking for property at affordable prices.

Currently it takes approximately 3.5 hours to drive to the new golf resorts from

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

thens, but this time will be reduce to under 3 hour when new road are in place. In accordance with the government’s guidelines for the ‘Good Road Plan’ a new motorway is under construction from Tropol

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

i to Kalamata and is nearly completed. Another new major road is planned between Kalamata and Methoni further opening up the area. There is also talk of expanding Kalamata airport although nothing has

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

been confirmed yet. However, demand for flights is already outstripping availability so it is only a matter of time before flights to Kalamata are increased.

Messinia is one of the most beautiful l

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

ocations in the whole of Greece. This lesser know region is full of cultural history, important archaeological sites and is rich in colourful, traditional towns and villages. It has an abundance of

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

outstanding natural beauty and some of the best beaches in the whole of Greece. It is hardly surprising, therefore, that Messinia has become an area of interest for golf enthusiasts and their families

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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