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    There are two types of houses you can buy from people in foreclosure: those with equity and those with no equity. T
    According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product
    his article is about a system I designed for those situations where the house you're looking to invest in has equit
    ; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

    Examples of combination products may in
    and the homeowner in foreclosure wants some cash for their equity.

    Let’s say there is $50k in equity. You’re goin
    lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

    to make an offer that includes $5,000 for the homeowner if the homeowner has brought up the need for cash to you.
    here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe
    You get the homeowner to agree to take $5,000 for the equity in the house. But the bank cannot know that the homeow
    d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

    Combination pro
    er is getting any amount of money or the deal is dead.

    This is where the Bill of Sale—or the "BOSS" System
    ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc
    omes in.

    Here’s an example of how this works:

    After negotiation, the homeowner has agreed to take $5,000 for $50,
    easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi
    000 worth of equity. You’ve done a good job, because you’re going to buy it at a discount.

    As you sit there with t
    nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically
    e homeowner, you explain the BOSS system like this:

    "Mr. Homeowner, you and I have come up with an agreement that
    and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ
    s acceptable for both of us. I agree to pay you $5,000 for your equity in the house. We agree on this, correct?"

    "
    ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi
    es."

    "However, you need to understand, the bank does not want to know that you’re getting any money. If they do, t
    ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

    Following aspects would a
    hey will reject the proposal.

    "So what I’d like to do is buy that television sitting right there for $5,000. I wi
    dd to the challenges in developing combination products:

    Which markets to tap where the combination products can do fairly well?
    Which combination prod
    l produce a bill of sale for that. I will pay you $5,000 for the television. And by the way, and I hope it’s ok wit
    cts are meaningful and rational?
    Which therapeutic categories to select?
    Which Combinations can address unmet needs of the patients?
    Do combin
    you, but if the television is not here when I come to the house, after you move, I’m not going to worry about it."
    tions increase the patient compliance?
    What would be the developing cost?
    How to tackle the risks encountered during combination product developmen


    So what you’re telling the homeowner is, you’re going to give him $5,000 for the deal, they take their TV, and yo
    t?

    As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel
    ’ve got a deal. You give them a promissory note for the TV for $5,000, contingent upon a successful sale of the pro
    ping new procedures for reviewing their safety, efficacy and quality.

    Professional from academic institutions, pharmaceutical industries, health care indust
    erty to your company. You give them a Bill of Sale as well, so you can record it as a transaction, as a cost of doi
    y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products
    ng business.

    Once the property is sold to your company, the homeowner can, if they have to, place a lien against t
    .

    As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de
    e property for $5,000 so just get them the money as quickly as you can. The homeowner wants to know that they’re go
    elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

    Companies that provide selfless information through particip
    ng to be protected. You tell them that you’re going to have that $5,000 for them upon the purchase of the property


    tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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