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    There has been a noticeable increase in the time taken for property speculators to 'flip' their condominium units. Why? Perhaps because, following an increase in constructi
    According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product
    on costs and off-plan sales prices, speculators are having to sell at a price to end users that may be prohibitively expensive, especially following several recent increase
    ; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

    Examples of combination products may in
    in interest rates and the associated increase in mortgage costs.

    When it comes down to it, some people don't feel completely comfortable in buying into a condominium that
    lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

    is still under construction. Perhaps they were stung during the 1997 economic collapse. Perhaps they are concerned that the same thing might happen again. There is of cours
    here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe
    e a level of risk involved. Property speculators take on this risk, and over recent years many may have profited well from doing so.

    However, given that there have been a
    d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

    Combination pro
    umber of new units entering the market over the last year, the supply of speculator driven 'resale units' in new condominiums has increased, which means that the end user w
    ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc
    ll commonly have a choice of a number of units in any one condominium, increasing the competition between speculators, and the end user is in a stronger position to negotia
    easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi
    te the price down. As such, for many property speculators, investments returns are not only taking longer to come to fruition, but the profit margin is also on the wane.
    nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically
    How are these speculators going to continue to make good profits? Where will they look next? Well, recently a speculator acquired a bare shell penthouse unit in an older co
    and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ
    dominium with the sole intention of renovating the unit and re-selling at a profit.

    The speculator employed a reputable interior renovation company to refurbish the unit i
    ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi
    it's entirely. As the unit was bare shell, it needed much more than just a fresh lick of paint. But, the purchaser was daring enough to take this challenge on, and after 3
    ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

    Following aspects would a
    months of renovation works, the unit was marketed and sold within 6 weeks at a profit of 30% of the total amount spent on the unit, including the renovation work.

    In fact
    dd to the challenges in developing combination products:

    Which markets to tap where the combination products can do fairly well?
    Which combination prod
    many individuals or companies make a good profit from looking around for a good deal, and then gutting the unit and making it look really nice; often not necessarily using
    cts are meaningful and rational?
    Which therapeutic categories to select?
    Which Combinations can address unmet needs of the patients?
    Do combin
    the highest grade materials, but looking really nice. The difference in achievable prices between units 'A', with the old Formica scratched fitted wooden furniture and smel
    tions increase the patient compliance?
    What would be the developing cost?
    How to tackle the risks encountered during combination product developmen
    ly carpet, and unit 'A' with the new modern furniture and bright shiny tile flooring and concealed lighting, could be as much as 40%.

    There are of course a whole number of
    t?

    As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel
    hurdles, pitfalls and two steps forward followed by one step back. You need a good team of interior decorators and most importantly a good supervisor or foreman at the helm
    ping new procedures for reviewing their safety, efficacy and quality.

    Professional from academic institutions, pharmaceutical industries, health care indust


    Even if you do manage to get the above, you would still be well advised to ensure that the work is regularly supervised, to make sure that the workmen are not mixing too
    y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products
    much sand with concrete to save costs etc. The other problem that is often experienced is when a 2 month fit out job ends up taking 6 months.

    Perhaps the best way to overc
    .

    As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de
    me this problem is by making sure that you get qualified references of the contractor before giving them the job, and be very 'hands-on' during the refurbishment period to
    elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

    Companies that provide selfless information through particip
    nsure that the project remains on time and within budget. So when you're next out property hunting, don't always judge a book by its cover, try to visualize what could be


    tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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