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I was talking with a very nice woman today on the phone about getting started wholesaling i

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

n real estate and she had some very good questions. One of them was about whose name actual

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

y goes on the contract when you are wholesaling.

I think, from what she said, that part of

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

her concern was liability and the other part was how the wholesaling process mechanically

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

orks. So, here is my brief overview of how we Wholesale and how I recommend you do it.

In

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

our business, our Independent Contractor Wholesalers go out and talk to motivated sellers w

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

o want or often need to sell their house. When we wholesale that house we typically have ou

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

r Independent Contractor Wholesalers present an offer from us to purchase the house.

The k

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

y here is that we also add, “AND/OR ASSIGNS” and make sure that the contract we are present

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

ing allows us to assign our rights in that contract to another buyer.

If you were wholesal

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

ng on your own (not as an Independent Contractor Wholesaler for us), you would use your bus

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

ness (or personal name if not operating as a business) on this contract.

Is there liabilit

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

y in signing a contract like this? Yes. Depending on the contract you use, the person who i

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

agreeing to buy may be risking their earnest money or may be liable to be sued by the sell

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

er to complete the sale.

We typically use earnest money contracts, but we also have a clau

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

e in the contract AND disclose to the seller that we will need some time to try to find our

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

buyer and that if we do not find our buyer in that time, then we both agree to cancel the

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

ontract and return our earnest money deposit to us.

So, as you can see, our risk is very s

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

mall in wholesaling real estate especially when you consider that we typically use $20 for

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

arnest money and often times we even use a promissory note for $20 instead of cash or check

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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