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Argentina is one of the most varied and interesting places to be found on the globe. A melting pot of nationalities populated the country in the 19th century and they have lef

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

t indelible marks on the country from the English Cricket Club at Buenos Aires, the Welsh in Patagonia, the Italian Chic and Parisian construction of the Capital city and the

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

organisational structure taken from the Spanish!

As many people know, Argentina defaulted on its foreign debt in 2001 and one of the effects was that the banks were closed an

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

people could not get access to their money. It was finally decided that the old order had to go, the politicians that had taken Argentina to this point and for once it wasn't

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

the military who took the action. New President Kirchner has steadied the ship despite the forced devaluation of the peso which previously traded at 1:1 with the dollar, is n

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

w at 3:1. Therefore life became a lot more expensive for Argentinians who earn in Pesos as everything from real estate through to cars became triple their previous price. Thin

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

gs that are priced in pesos remained the same apart from the relatively high inflation rate which is now being dealt with.

Investors therefore had and are having a field day.

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

Suddenly there was a fire sale of properties because people couldn't get their money from the banks and prime real estate was being sold off at bargain basement prices. Those

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

who came in taking both the long and medium term view are currently enjoying increases in their investments of over 200% compared with the prices in 2001-2.

Buenos Aires real

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

estate is booming with increase reported of up to 37% in the year to October 2006 and the rest of the country is enjoying the boom that the trickle down effect creates from Bu

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

enos Aires.

The Mendoza province is the huge wine growing area and is considered a paradise on Earth by some. Patagonia is enjoying a tourist boom to what they describe as a

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

huge Lake District. Argentinians now take their beach holidays in Las Grutas where the warm waters lap up giving it a large advantage over other areas at these latitudes and A

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

gentina shares part of the Iguazu Falls, the most spectacular waterfalls in the World probably which is now being developed for tourism.

The country is fantastic, the culture

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

is a melting pot, part Italian, part Spanish in its majority but there is a part of Patagonia where Welsh is spoken by a whole community, the remnants of a business in cattle

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

and sheep from many years ago (Even the place names are in Welsh)

The economy of the country is basically sound now that the old order and corruption have been eased out of p

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

ower. It is based on land, lots of it, meat, wines, cash crops, and possibly most importantly oil. The area around Neuquen is a huge oil field meaning that petrol in Argentina

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

is around 30p per litre (if you can afford a car which of course are priced in dollars)

Valencia Property S.L is offering a tract of land by the beach in Las Grutas in Rio Ne

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

gro province. It is the perfect place to construct holiday villas or small hotels as demand is multiplying in the area year on year and looks to continue that way for the medi

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

m term future. This is the area that middle class Argentinians are flocking to in their droves for investment and holidays since they cannot now afford the USA. The plots we a

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

re selling are priced at between 12 and 13500 Euros and building on the plots will be relatively inexpensive too with a 100m2 house expected to be built for around 40000 Euros

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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