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What is the working protocol of journalism especially for magazines? Also what is the role of editor-in-chief in a magazine and the working hierarchy in a magazine... who reports to whom? Also how much should the

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

editor-in-chief allow the owners/publishers/directors of the media company to interfere in the editorial content? These are just some of the questions that is normally asked about the inner workings of a magazin

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

e.

First, I'm not sure what you mean by "working protocol of journalism." Are you talking about relationships with sources, between editors and reporters, or something else? In the context of your other question

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

, I wonder if you mean something to do with editorial authority, too.

Second,Various journalism roles can vary quite a bit, actually, from publication to publication. Some companies have more "hands-on" manageme

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

nt styles, while others give their executives more autonomy. But, in general, the editor-in-chief has control over the publication's editorial contents and direction, just as the advertising director has control

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

over the ad contents, placement, and policies.

That doesn't mean the editor is God, because he/she shares power with other high-ranking executives. The editor's greatest management skill is in working effectivel

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

with people -- knowing how to negotiate with other power brokers who have a say in how the magazine is put together, distributed, etc.

I'll give you an example of hierarchy: In the trade magazine publishing com

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

pany where I worked, there was an individual editor over each magazine. We shared a pool of in-house writers, and we each contracted separately with freelancers as needed. There also was an advertising director w

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

ho managed the ad sales and placement for each of the three magazines. If I didn't like the ad placement in my magazine, I could go to her and negotiate; she was usually agreeable within reason.

(Of course, we u

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

ually prevented negotiations by talking in advance about special features that would need special space, and she was conversant with our standard placement of recurring features, etc.) We also worked with execs a

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

t various support companies -- R.R.

Donnelley printing in Senatobia, Miss., which required us to meet certain format standards with what we submitted and to adhere to agreed-upon timetables; and the company that

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

wrapped, labeled, and mailed our magazines, which required clear directives, correct mailing label files, and adherence to agreed-upon timetables. We also worked with the business office in our publishing compan

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

to communicate clearly about incoming bills from freelancers (then signing off on them) and other issues.

In other words, the hierarchy is broader, and less linear, than I thought it would be from my studies in

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

journalism. The real world is much, much, much more "cooperative" than it is territory based. And, sadly for editors, the power tends to reside where the money is (hint: Not in the editorial offices). Often, the

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

ad director swings a bigger stick than you will as an editor. Make close friends with the ad director -- do favors when you can. You'll need to call those favors in at some point. Make sure you develop a relatio

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

ship as allies rather than as adversaries.

Last, The editor-in-chief has limited options in how much he lets the magazine's owners, publishers, and other higher-ups interfere with the editorial content. He shoul

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

d establish the extent of his authority when he is hired and, if possible, have it spelled out in writing. Clear upfront communications are the best preventative step. He can help prevent problems by communicatin

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

g clearly with his bosses about editorial directions and getting buy-in as he goes along rather than waiting for issues to arise.

If issues are raised later on, the editor's best tool is to be persuasive to his

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

osses and help them understand why his editorial judgment should prevail. However, when push comes to shove, the editor's choices are limited: Stay and bow to his boss's wishes, violate his boss's wishes and take

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

the consequences, or quit. If he has an employment contract that has been violated, he may consider suing, but that would be rare. Often, compromise (within the limits of your personal ethics) is the best option

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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