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The other day my son said to me, what else could anyone possibly invent? Sometimes it would seem that way, but I think that couldn’t be further from the truth

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

. Back in the late sixties and early seventies someone realized that light emitting diodes could be used for indicator lights. They only were available in the

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

color red, but that didn’t stop anyone, in fact we all became quite familiar with that red color in things like calculators and hand held games. That is pret

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

y much where LED’s stayed until a few years ago.

Suddenly LED’s were available in different colors. A new super bright LED was developed. Controllers made co

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

lor changing possible as well as mixing colors to create almost any color in the spectrum. A whole new market is emerging now. Many municipalities have starte

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

to change over the traffic lights to LED bulbs. I am sure you have seen them; they appear as many small dots of light for the Red and the Green. Car manufact

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

urers are using them inside indicator lights.

The most exciting aspect of LED lighting for me is the entrance of LED’s into residential lighting. They can be

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

used for accent lighting in many applications such as under cabinet lighting and inside cabinets. Cove lighting is another application where they can be used

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

There are LED bulbs that can replace some existing bulbs like an MR 16 low voltage bulb.

As of right now in their development accent lighting is where they

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

are best suited, the time for them to replace conventional light bulbs is not far off. As an example of where LED’s can really shine is a pool light that can

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

hange into seven different colors just by turning the regular switch on and off to change modes. There are other types of color changing bulbs that can be use

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

d for decorative purposes. If you want to do some really creative lighting projects, you need to look into LED’s.

If your wondering what is so great about LE

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

D’s, let me explain. They have great advantages over conventional light bulbs. Here is a list of just a few things:

· Huge energy savings, possibly as high a

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

80% - 90%
· Very long life some claims as high as 100,000 hours
· Durable and resistant to heat, cold, shock and vibration
· Endless color pos

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

sibilities
· Instant on with no flickering
· Small size allows lights in tight spaces
· Almost no heat and no UV rays

The one place they still

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

are weak in is general lighting use. When they have that ability though the energy savings will be on a huge scale. The traffic lights I mentioned earlier use

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

a 10 watt LED bulb to replace a 150 watt bulb used in the past. To give you an idea how much this saves at 12.5 cents a KWH, the savings for a single bulb in

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

one year is about $75. Pretty amazing, especially when you consider some 150,000 traffic lights across the country have been retrofitted with these new LED l

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

ght bulbs. That is an energy savings of over 11 million dollars. (c)Paul Forte 2005

If you would like to know more or see some of the great LED products av

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

ailable, follow the link below or visit http://www.forteelectric.com/LEDlighting.html

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

Essential reading for business owners. Retired financial executive explains how the banker views your business loan application, and collateral, so you know how to present it. One of a series of articles to help business owners succeed in understanding how to optimize their financing and keep their banker happy!

Effective small business marketing is the lifeblood of any small business. It starts with being able to write a simple and practical marketing plan, specifically for your business.

The help that is offered by members of forums never ceases to amaze me. Online home business help is available in so many areas that it is possible to have all ones queries and problems sorted out by individuals willing to give freely of their time.

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