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Global Positioning Systems (GPS) was originally developed by the US Armed Forces to help with naval and overland navigation. GPS uses a constell

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

ation of satellites to beam down encoded time signatures to receivers on the surface. By tracking the delay between when the time code says the s

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

gnal was sent and when it actually arrived, GPS uses Einstein's theory of relativity and four signals (three if altitude is known) to provide acc

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

rate tracking down to about two meters. GPS technology has been moving into the commercial sphere from the military since the 1990s.

GPS fleet t

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

acking systems are used in public transportation, most notably school buses in Kansas City and New York City. These systems allow school district

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

to know exactly where each bus is, thus improving the safety of their passengers. On flex routes, GPS gives drivers some leeway in adjusting the

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

r course to avoid traffic congestion. The secondary benefit is that it allows the school districts in question to better assess idle times, bett

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

er routing algorithms and fuel efficiency. School officials and parents have a peace of mind knowing that the school buses are monitored constant

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

y.

In April 2007, a private taxi company launched a fleet of 150 GPS-enabled metered taxis (or Meru taxis) in Mumbai, India. Customers will be

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

ble to call for a taxi at to pick up at a preferred location and book in advance on the phone or internet. If a customer accidentally left any pe

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

sonal item in a taxi, this GPS technology can track to the specific taxi quickly and easily. All collected Meru taxi fares are transmitted back t

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

the control centre and monitored to ensure that customers are charged appropriately. The company plans to increase the fleet to 1,000 taxis by y

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

ar end.

In the commercial sector, GPS is used for tracking delivery trucks and trucks used by contractors going to job sites. This allows real

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

ime monitoring of what trucks are en route and better tracking of actual mileage used (versus what's billed for). This also increases fleet wide

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

fuel economy, and allows employers to check the actual hours driven by drivers in a day for mileage bonuses and "drive time" pay. H.A. Sun Heat

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

ng and Cooling Inc. of Bloomfield, Mich. is an example of a company that installed GPS fleet tracking system in every of its truck. The company i

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

able to access real time information that leads to savings in manpower costs (from people claiming they were on a shift for 8 hours, when the GP

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

showed that they'd only driven for seven and a half), reduced fuel costs and increased productivity and efficient truck routing. For this compan

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

, the GPS paid for itself in 30 days.

GPS fleet tracking system has been proven to increase efficiency and productivity in all types of business

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

s that own fleet of vehicles. In addition to cost and time savings, customer satisfaction is significantly improved through better responsiveness

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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