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Just as it has revolutionized the television industry, high definition technology is now changing the way we listen to the radio. High definition

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

radio (HD-radio) makes tuning into your favorite station a whole new experience. Using high definition technology, any station in the country can

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

deliver super, CD-like sound to its audience. High definition technology also makes it possible for listeners to receive information services such

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

as traffic and weather alerts and stock information on their radios.

Pioneered by a company called iBiquity Digital, HD-radio was created in res

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

ponse to satellite radio, which, in the mid-90s, posed a real threat to traditional, or analog, radio. HD-radio mixes digital signals and analog s

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

ignals, a combination that has made it possible for traditional stations to embark on the inevitable conversion to digital. In 2002, iBiquity made

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

its HD-radio technology available to networks around the nation, and many of them jumped at it.

HD-radio offers a host of enhancements to tradit

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

ional stations, and iBiquity says the following improvements are possible:

-In terms of sound quality, AM radio will sound like FM radio.

- FM r

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

adio will have crystal clear, CD-like sound

- Reception will be free of static, free of white noise, and station loss will no longer be a problem

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

.

- Special services like On-Demand radio will be possible for listeners with HD-Radio. Wireless services will deliver news and traffic updates.

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

These upgrades are available to networks for about $250,000. Now, about 300 broadcasters are utilizing HD-radio. Thousands more should follow in

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

the next few years. When they do go high def, they’ll still be able to broadcast in traditional, analog fashion. The ability to transmit digital s

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

ignals is a big step for networks, but one that seems inevitable, given the improvements that result. Thanks to HD technology, some stations are n

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

ow providing different kinds of programming from a single spot on the radio dial.

Fans of traditional radio should embrace HD technology because

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

it delivers better audio quality and more options for listening. HD-radio is also free. Listeners don’t have to go through a subscription service

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

to get it, and they won’t have to worry about receiving upgrades from their providers. However, listeners will need to purchase special components

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

for HD-radio and find stations that are broadcasting in HD.

Added bonuses with HD broadcasting include the display of weather, news and song inf

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

o on the screen of the radio. Listeners can also buy music through their HD systems, and they’ll have access to special recording options for musi

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

c. High definition radios are becoming more and more common. They’re currently priced at about $150. Automobile manufacturers have started to inst

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

all them in new cars. Plans are even in the works to apply high definition technology to MP3 players and cell phones. What will they think of next

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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